Brilliance may refer to:

• Brilliance (gemstone), a measure of the light performance of gemstone diamonds
• Brilliance, a bitmap graphics editor for the Amiga
• Brilliance, the quality of an x-ray source
• Brilliance , 1982
• Brilliance, an album by Chieko Kawabe, 2005
• The Brilliance, an American indie band
• Brilliance Audio, an ebook subsidiary of Amazon
• Brilliance Auto, a Chinese car company
• Brilliance, a novel by Marcus Sakey, 2013
• Genius